Journal of Medicinal Chemistry p. 1139 - 1169 (2021)
Update date:2022-08-03
Topics:
Marcyk, Paul T.
Leblanc, Emmanuelle V.
Kuntz, Douglas A.
Xue, Alice
Ortiz, Francisco
Trilles, Richard
Bengtson, Stephen
Kenney, Tristan M. G.
Huang, David S.
Robbins, Nicole
Williams, Noelle S.
Krysan, Damian J.
Privé, Gilbert G.
Whitesell, Luke
Cowen, Leah E.
Brown, Lauren E.
The essential eukaryotic chaperone Hsp90 regulates the form and function of diverse client proteins, many of which govern thermotolerance, virulence, and drug resistance in fungal species. However, use of Hsp90 inhibitors as antifungal therapeutics has be
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