
Journal of the Chemical Society. Chemical communications p. 486 - 488 (1980)
Update date:2022-08-04
Topics:
Kelleher, Roger G.
McKervey, M. Anthony
Vibuljan, Pongsak
Anhydrous lithium iodide in ether, tetrahydrofuran, or benzene is an effective reagent for the formation of α,β-unsaturated ketones by condensation of alkyl ketones with enolisable and non-enolisable aldehydes; in the presence of trimethylchlorosilane-triethylamine enone formation is suppressed and high yields of 1,3-hydroxyketones are obtained as their trimethylsilyl ether derivatives.
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