Bioorganic and Medicinal Chemistry Letters p. 2687 - 2690 (2000)
Update date:2022-09-26
Topics:
Perni, Robert B.
Conway, Samuel C.
Ladner, Stephanie K.
Zaifert, Katie
Otto, Michael J.
King, Robert W.
A non-nucleoside class of compounds that inhibits the replication of hepatitis B virus (HBV) in cell culture has been discovered. A series of substituted analogues of phenylpropenamide 6 has been prepared and evaluated in the HepAD38 cellular assay. Structure-activity relationships of this series are discussed. (C) 2000 Elsevier Science Ltd.
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