Oligonucleotides covalently linked to an acridine at artificial abasic site: Influence of linker length and the base-sequence

DOI: 10.1016/0040-4039(96)00989-6

Source and publish data:

Tetrahedron Letters p. 4983 - 4986 (1996)

Update date:2022-08-04

Topics:

Authors:

Fukui, Keijiro

Iwane, Kazunori

Shimidzu, Takeo

Tanaka, Kazuyoshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(96)00989-6

Oligonucleotides covalently linked to an 9-amino-6-chloro-3- methoxyacridine via pore a trimethylene to pentamethylene linker were prepared using novel L-threoninol backbone phospharamidites. Although all of the modified oligonucleotides could bind to the

Full text of DOI:10.1016/0040-4039(96)00989-6

Products guided by the article

Product name:5-(6-Chloro-2-methoxy-acridin-9-ylamino)-pentanoic acid {(1R,2R)-1-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2-hydroxy-propyl}-amide

Cas No:850589-22-9

R&D Labs maybe for 850589-22-9

Mascot I.E. Co., Ltd.

website:http://www.mascot-ie.com

Contact:86-519-85010339

Address:B-802,XingBei Building,391#,Tongjiang Middle Road New District,Changzhou,JS,China
Shijiazhuang Yunxuan Im&Export Co.,Ltd.

Contact:+86-311-83037514

Address:No.6 Hongbin Road
Shangyu Sanhechemicals Co.,LTD.

Contact:86-0571-56696839

Address:Num.2952,Nanhuan Road,Binjiang District,Hangzhou,China
Nowa pharmaceuticals Co., LTD

Contact:86-512-69362780,69362785

Address:No.69 Weixin Road,Weiting Town,Suzhou Industrial Park
jintan yufan Medicine Raw materials Co.,Ltd.(expird)

Contact:86-519-82808282

Address:6th,Jincheng Huangzhuang

Relevant to this article

Photochemical generation of ribose abasic sites in RNA oligonucleotides

Doi:10.1021/ol050120h
(2005)
Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu ₄ positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)

Doi:10.1016/j.bmcl.2010.07.007
(2010)
Five new zinc phosphite structures: Tertiary building blocks in the construction of hybrid materials

Doi:10.1021/ic048204u
(2005)
Reactions of (PCP)Ru(CO)NHPh(PMe₃) (PCP = 2,6-(CH ₂P^tBu₂)₂C₆H₃) with substrates that possess polar bonds

Doi:10.1021/ic0483592
(2005)
Insight into Transannular Cyclization Reactions to Synthesize Azabicyclo[X.Y.Z]alkanone Amino Acid Derivatives from 8-, 9-, and 10-Membered Macrocyclic Dipeptide Lactams

Doi:10.1021/acs.joc.5b00237
(2015)
Systematic study of the synthesis of macrocyclic dipeptide β-turn mimics possessing 8-, 9-, and 10- membered rings by ring-closing metathesis

Doi:10.1021/jo0477648
(2005)

Article Doi