STRUCTURE AND SYNTHESIS OF REDUCTILINE, A NOVEL METABOLITE FROM A VARIANT OF STREPTOMYCES ORIENTALIS

DOI: 10.1016/S0040-4039(00)85765-2

Source and publish data:

Tetrahedron Letters p. 4977 - 4980 (1982)

Update date:2022-08-04

Topics:

Authors:

Ojika, Makoto

Shizuri, Yoshikazu

Niwa, Haruki

Yamada, Kiyoyuki

Iwadare, Shuichi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)85765-2

The structure of reductiline, a metabolite of a variant of Streptomyces orientalis was elucidated as (1) based on chemical and spectroscopic evidence.Transformation of an antitumor antibiotic reductiomycin (2) into reductiline (1) was carried out.Synthesis of reductiline (1) was achieved starting from β-cyanopropionaldehyde dimethylacetal.

Full text of DOI:10.1016/S0040-4039(00)85765-2

Products guided by the article

Product name:(E)-N-(2-Hydroxy-5-oxo-1-cyclopentene-1-yl)-3-[1-[3-(methylthio)propyl]-1H-pyrrole-3-yl]propenamide

Cas No:85145-25-1

R&D Labs maybe for 85145-25-1

BOC Sciences

website:https://www.bocsci.com/

Contact:1-631-485-4226

Address:Ramsey Road
Tai zhou world Pharm & Chem Co., Ltd

Contact:+86-576-85301198

Address:Rome 1001,wangjiang plaza,unti 2,jinshan east Road linhai,zhejiang,china
EGBERT CORPORATION

Contact:+86 18616952870

Address:Area
Guangxi Shanyun Biochemical Science and Technology Co., Ltd

Contact:+86-0772--6828887

Address:#2 Industrial Park of Luzhai County, Liuzhou, Guangxi, China
GenicBio Limited

Contact:+86-(0)21-3770 9035

Address:Room 301, Building 2, Meijiabang Road 1508, Shanghai China

Relevant to this article

Synthesis of biologically relevant compounds by ruthenium porphyrin catalyzed amination of benzylic C-H bonds

Doi:10.1021/om500064d
(2014)
Preparation of fluorine-containing exo- and endocyclic enamine derivatives of 2-acylcyclopentane-1,3-diones

Doi:10.1134/S1070363214030098
(2014)
3,3-Difluoro-3,4,5,6-tetrahydropyridin-2-amines: Potent and permeable BACE-1 inhibitors

Doi:10.1016/j.bmcl.2020.126999
(2020)
N-Bridged 1-deoxynojirimycin dimers as selective insect trehalase inhibitors

Doi:10.1016/j.carres.2013.12.025
(2014)
Synthesis, crystal structure and biological evaluation of some novel 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles and 1,2,4-triazolo[3,4-b]-1,3,4- thiadiazines

Doi:10.1016/j.ejmech.2014.03.046
(2014)
Synthesis, structure, and catalytic activity of new ruthenium(II) indenylidene complexes bearing unsymmetrical N - heterocyclic carbenes

Doi:10.1021/om4009197
(2014)

Article Doi