STRUCTURE AND SYNTHESIS OF REDUCTILINE, A NOVEL METABOLITE FROM A VARIANT OF STREPTOMYCES ORIENTALIS

DOI: 10.1016/S0040-4039(00)85765-2

Source and publish data:

Tetrahedron Letters p. 4977 - 4980 (1982)

Update date:2022-08-04

Topics:

Authors:

Ojika, Makoto

Shizuri, Yoshikazu

Niwa, Haruki

Yamada, Kiyoyuki

Iwadare, Shuichi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)85765-2

The structure of reductiline, a metabolite of a variant of Streptomyces orientalis was elucidated as (1) based on chemical and spectroscopic evidence.Transformation of an antitumor antibiotic reductiomycin (2) into reductiline (1) was carried out.Synthesis of reductiline (1) was achieved starting from β-cyanopropionaldehyde dimethylacetal.

Full text of DOI:10.1016/S0040-4039(00)85765-2

Products guided by the article

Product name:(E)-N-(2-Hydroxy-5-oxo-1-cyclopentene-1-yl)-3-[1-[3-(methylthio)propyl]-1H-pyrrole-3-yl]propenamide

Cas No:85145-25-1

R&D Labs maybe for 85145-25-1

CHEM PLUS

Contact:0027-717-456976

Address:2ND FLOOR, 325 VAUSE ROAD, OVERPORT, 4001, SOUTH AFRICA
Li's chemicals

Contact:+86-15850770348

Address:51 OF XIANGFANGCUN ROAD, Nanjing 210002, China
Shanghai Massive Chemical Technology Co., Ltd.

website:http://www.massivechem.com/

Contact:+86 21 34943721

Address:Room 435, 4th floor, Building 9, No. 2568 Gudai Road,Minhang District, Shanghai,
Jintan City Mego Chemical Co., Ltd

Contact:+86-0519-82814387

Address:23# Dengguan Town, Jintan, Jiangsu Province, China
HUNAN CHEMAPI BIOLOGICAL TECHNOLOGY CO.,LTD.

Contact:+86-186-02659358

Address:1004, building 3, Wanke Jinsemaitianyuan, 498 Guitang Road, Yuhua District, Changsha City, Hunan Province, China

Relevant to this article

Synthesis of biologically relevant compounds by ruthenium porphyrin catalyzed amination of benzylic C-H bonds

Doi:10.1021/om500064d
(2014)
Preparation of fluorine-containing exo- and endocyclic enamine derivatives of 2-acylcyclopentane-1,3-diones

Doi:10.1134/S1070363214030098
(2014)
3,3-Difluoro-3,4,5,6-tetrahydropyridin-2-amines: Potent and permeable BACE-1 inhibitors

Doi:10.1016/j.bmcl.2020.126999
(2020)
N-Bridged 1-deoxynojirimycin dimers as selective insect trehalase inhibitors

Doi:10.1016/j.carres.2013.12.025
(2014)
Synthesis, crystal structure and biological evaluation of some novel 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles and 1,2,4-triazolo[3,4-b]-1,3,4- thiadiazines

Doi:10.1016/j.ejmech.2014.03.046
(2014)
Synthesis, structure, and catalytic activity of new ruthenium(II) indenylidene complexes bearing unsymmetrical N - heterocyclic carbenes

Doi:10.1021/om4009197
(2014)

Article Doi