STRUCTURE AND SYNTHESIS OF REDUCTILINE, A NOVEL METABOLITE FROM A VARIANT OF STREPTOMYCES ORIENTALIS

DOI: 10.1016/S0040-4039(00)85765-2

Source and publish data:

Tetrahedron Letters p. 4977 - 4980 (1982)

Update date:2022-08-04

Topics:

Authors:

Ojika, Makoto

Shizuri, Yoshikazu

Niwa, Haruki

Yamada, Kiyoyuki

Iwadare, Shuichi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)85765-2

The structure of reductiline, a metabolite of a variant of Streptomyces orientalis was elucidated as (1) based on chemical and spectroscopic evidence.Transformation of an antitumor antibiotic reductiomycin (2) into reductiline (1) was carried out.Synthesis of reductiline (1) was achieved starting from β-cyanopropionaldehyde dimethylacetal.

Full text of DOI:10.1016/S0040-4039(00)85765-2

Products guided by the article

Product name:(E)-N-(2-Hydroxy-5-oxo-1-cyclopentene-1-yl)-3-[1-[3-(methylthio)propyl]-1H-pyrrole-3-yl]propenamide

Cas No:85145-25-1

R&D Labs maybe for 85145-25-1

Lian Xing Chemical Co.,Ltd.

Contact:0792-8228321

Address:10TH Floor No.121 binjiang Road Xunyang District
Tianjin Jiuri New Materials Co., Ltd.

Contact:+86-22-58889220

Address:C-5/6, Vison Hill, No.1 Gonghua Road, Huayuan Hi-tech Park, Tianjin, China.
Shanghai Pengkai Chemical Co.,Ltd

Contact:+86-21-60526671

Address:No.4226 Duzhuang Rd Minhang District Shanghai China
Suzhou Time-chem Technologies Co., Ltd.

Contact:0512-63983931/68086856

Address:No. 1326 of Binhe Road, New District, Suzhou, Jiangsu, P. R. China
Jiangsu Seed Chem Co.,Ltd.

Contact:86-513-84128750/13773795976

Address:No.48.Youyi West Road ,Rudong Development Zone,Jiangsu Province,China

Relevant to this article

Synthesis of biologically relevant compounds by ruthenium porphyrin catalyzed amination of benzylic C-H bonds

Doi:10.1021/om500064d
(2014)
Preparation of fluorine-containing exo- and endocyclic enamine derivatives of 2-acylcyclopentane-1,3-diones

Doi:10.1134/S1070363214030098
(2014)
3,3-Difluoro-3,4,5,6-tetrahydropyridin-2-amines: Potent and permeable BACE-1 inhibitors

Doi:10.1016/j.bmcl.2020.126999
(2020)
N-Bridged 1-deoxynojirimycin dimers as selective insect trehalase inhibitors

Doi:10.1016/j.carres.2013.12.025
(2014)
Synthesis, crystal structure and biological evaluation of some novel 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles and 1,2,4-triazolo[3,4-b]-1,3,4- thiadiazines

Doi:10.1016/j.ejmech.2014.03.046
(2014)
Synthesis, structure, and catalytic activity of new ruthenium(II) indenylidene complexes bearing unsymmetrical N - heterocyclic carbenes

Doi:10.1021/om4009197
(2014)

Article Doi