Synthesis of Chain-Extended and C-6' Functionalized Precursors of the Nucleoside Antibiotic Sinefungin

DOI: 10.1021/jo00160a008

Source and publish data:

Journal of Organic Chemistry p. 1982 - 1988 (1983)

Update date:2022-08-04

Topics:

Authors:

Lyga, John W.

Secrist, John A.

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Article abstract of DOI:10.1021/jo00160a008

Precursors of sinefungin were prepared by chain extension of the blocked adenosine 5'-aldehyde 4 through a carbon-carbon bond to C-5'.Bond formation was accomplished with variously functionalized stabilized ylides.Employment of 2-oxo-3-(triphenylphosphora

Full text of DOI:10.1021/jo00160a008

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