Synthesis and biological activity of 8a-phenyldecahydroquinolines as probes of PCP's binding conformation. A new PCP-like compound with increased in vivo potency

DOI: 10.1021/jm00087a020

Source and publish data:

Journal of Medicinal Chemistry p. 1634 - 1638 (1992)

Update date:2022-09-26

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Authors:

Chen Chen

Kozikowski

Wood Wood

Reynolds

Ball Ball

Pang Pang

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Article abstract of DOI:10.1021/jm00087a020

The synthesis and chemical resolution of cis- and trans-fused 8a- phenyldecahydroquinolines 3 and 4 are described together with the affinity of the four optically pure compounds for the PCP recognition site of the NMDA receptor complex. These compounds we

Full text of DOI:10.1021/jm00087a020

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