Journal of the American Chemical Society p. 2706 - 2711 (1987)
Update date:2022-08-03
Topics:
Magnus, Philip
Gallagher, Timothy
Schultz, James
Or, Yat-Sun
Ananthanarayan, T.P.
The total synthesis of the unprotected A portion of the potent cytotoxic agent CC-1065 1 using the 3,3'-bipyrrole strategy is described.Treatment of ethyl sorbate with (p-tolylsulfonyl)methyl isocyanide (TosMIC)/NaH gave the pyrrole 7, which was N'-phenyl
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