Archiv der Pharmazie p. 431 - 434 (1983)
Update date:2022-09-26
Topics:
Hajela Km.
Sengupta
Shanker
Doval
Sixteen new 2-(phenoxyacetylthio)-3-aryl-6-bromo- or -6,8-dibromoquinazolines were synthesized by condensation of various phenoxyacetyl chlorides with mercaptoquinazolines. Their inhibitory properties towards choline esterase and their bactericidal activities were studied in vitro. Nine of the compounds exhibited (>50%) choline esterase inhibition, whereas the antibacterial screening showed moderate results.
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