Concise and diastereoselective approach to syn- and anti-N-tosyl-α- hydroxy β-amino acid derivatives

DOI: 10.1016/j.tet.2005.04.054

Source and publish data:

Tetrahedron p. 6546 - 6552 (2005)

Update date:2022-08-05

Topics:

Authors:

Zhao, Yonghua

Jiang, Nan

Chen, Shufeng

Peng, Cheng

Zhang, Xiaomei

Zou, Yaping

Zhang, Shiwei

Wang, Jianbo

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Article abstract of DOI:10.1016/j.tet.2005.04.054

The methyl diazoacetate and aryl (N-tosyl)imines can be transformed into syn or anti α-hydroxy β-amino esters with high diastereoselectivities in three steps: the base promoted nucleophilic condensation of the methyl diazoacetate and aryl (N-tosyl)imines

Full text of DOI:10.1016/j.tet.2005.04.054

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