STEREOSPECIFIC AND NON-HAZARDOUS SYNTHESIS OF CIS AND TRANS-3-PHENOXYACETAMIDO-4-(2-ACETOXY-1,1-DIMETHYLETHYL)-AZETIDIN-2-ONES KEY INTERMEDIATES FOR THE SYNTHESIS OF 6-AMIDO-1,1-DIMETHYL-CARBAPEN-2-EMS

DOI: 10.1016/S0040-4039(00)81348-9

Source and publish data:

Tetrahedron Letters p. 135 - 138 (1983)

Update date:2022-08-05

Topics:

Authors:

Chu, Daniel T. W.

Lester, David

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Article abstract of DOI:10.1016/S0040-4039(00)81348-9

The title compounds have been prepared by a four-step sequence from 3-acetoxy-2,2-dimethyl-1-propanal and a novel non-hazardous and stereospecific route to cis-3-amido-azetidin-2-ones by the use of N-benzyl-2-carbobenzoxyglycine is described.

Full text of DOI:10.1016/S0040-4039(00)81348-9

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