A selective synthesis of 3,6-dihydro-7H-1,2,3-triazolo[4,5-d]pyrimidin-7- ones

Article abstract of DOI:10.1246/cl.2005.1022

The carbodiimides 2, obtained from aza-Wittig reactions of iminophosphorane 1 with aromatic isocyanates, reacted with primary amine RNH₂ (R ≠ H, Me) to produce isolable guanidine intermediates 3, which were further treated with sodium ethoxide