EFFECT OF CONFORMATION AND STEREOCHEMISTRY IN SUBSTITUTION REACTIONS OF FUSED CHLOROCYCLOBUTANONES: OXYALLYL CATION INTERMEDIATES

Article abstract of DOI:10.1016/S0040-4039(00)86385-6

Fused α-acyloxycyclobutanones, whose conformation and stereochemistry have been unambiguosly established by X-ray analysis, undergo an unususal displacement with methoxide as nucleophile to produce α-methoxycyclobutanones.The success of this reaction, whi