Highly regioselective lipase-catalyzed acetylation and hydrolysis of acyclic α,α′-alkenediols and their diacetates

Article abstract of DOI:10.1016/j.tetlet.2005.07.039

Highly regioselective transformation of acyclic α,α′- alkenediols and their corresponding diacetates to monoacetates using lipase was accomplished. The acetylation of the α,α′-alkenediol regioselectively gave (E)-monoacetate, whereas the (Z)-monoacetate were obtained by hydrolysis of the α,α′-diacetate.