Tetrahedron Letters p. 7771 - 7774 (1995)
Update date:2022-08-03
Topics:
Nangia, A.
Chandrakala, P. S.
Pyrimidinone 4 is converted to diazetidinone carboxaldehyde 6.Selective chemical transformations on tricarbonyl substrate 6 with different reagents are performed.Synthon 6 is employed as a versatile template for elaboration to bicyclic diazetidinones 7, 12 and 15.A novel class of aza-β-lactam compounds are synthesised as potential transpeptidase and β-lactamase inhibitors.
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