A NEW AND GENERAL PROCEDURE FOR THE PREPARATION OF DEOXYNUCLEOSIDE PHOSPHORAMIDITES

DOI: 10.1016/S0040-4039(00)81817-1

Source and publish data:

Tetrahedron Letters p. 1963 - 1966 (1983)

Update date:2022-09-26

Topics:

Authors:

Fourrey, Jean-Louis

Varenne, Jeanette

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Article abstract of DOI:10.1016/S0040-4039(00)81817-1

Nucleoside phosphoramidites can be obtained in a one pot reaction by reacting successively an alkyloxy (or aryloxy)bis-triazolylphosphine with 3'-OH free deoxynucleoside and a trimethylsilylated secondary amine.

Full text of DOI:10.1016/S0040-4039(00)81817-1

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