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A NEW AND GENERAL PROCEDURE FOR THE PREPARATION OF DEOXYNUCLEOSIDE PHOSPHORAMIDITES

DOI: 10.1016/S0040-4039(00)81817-1

Source and publish data:

Tetrahedron Letters p. 1963 - 1966 (1983)

Update date:2022-09-26

Topics:

Authors:

Fourrey, Jean-LouisFourrey, Jean-Louis

Varenne, JeanetteVarenne, Jeanette

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Article abstract of DOI:10.1016/S0040-4039(00)81817-1

Nucleoside phosphoramidites can be obtained in a one pot reaction by reacting successively an alkyloxy (or aryloxy)bis-triazolylphosphine with 3'-OH free deoxynucleoside and a trimethylsilylated secondary amine.

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Full text of DOI:10.1016/S0040-4039(00)81817-1

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Product name:Dimethyl-phosphoramidous acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester

Cas No:86733-57-5

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