Archiv der Pharmazie p. 520 - 524 (1983)
Update date:2022-08-03
Topics:
Knabe, Joachim
Weirich, Wigand
The synthesis of the isoquinolines 2 and 3 is described.They were to be combined by the Ullmann reaction to yield the ether 1.Despite many variations of the reaction conditions, 1 was formed in traces only.The main reaction is the dehalogenation of the isoquinoline 3.The use of N-formyltetrahydroisoquinoline 9 instead of 3 was not successful, either.
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(2005)Doi:10.1021/jo0512608
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