Organic Letters p. 4919 - 4922 (2005)
Update date:2022-09-26
Topics:
Li, Xueshu
Zhang, Dongwei
Pang, Hai
Shen, Feng
Fu, Hua
Jiang, Yuyang
Zhao, Yufen
(Chemical Equation Presented) We have developed a general and efficient approach to a diverse series of phosphacoumarins as analogues of coumarins with various biological activities, and the inhibitory activity of the synthesized phosphacoumarins against the enzyme SHP-1, a protein tyrosine phosphatases, was tested. Some of them showed moderate to good efficiency.
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