Bioorganic and Medicinal Chemistry p. 4241 - 4252 (2006)
Update date:2022-09-26
Topics:
Ikura, Masahiro
Nakatani, Shingo
Yamamoto, Shingo
Habashita, Hiromu
Sugiura, Tsuneyuki
Takahashi, Kanji
Ogawa, Koji
Ohno, Hiroyuki
Nakai, Hisao
Toda, Masaaki
A series of N-benzoyl γ-aminobutyric hydroxamic acids were synthesized and evaluated as matrix metalloproteinase inhibitors. First, we focused on chemical modification of the N-benzoyl residue. Introduction of electron-rich para-substituents was effective
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