Journal of the American Chemical Society p. 6622 - 6629 (1983)
Update date:2022-08-03
Topics:
Overman
Kakimoto
Okazaki
Meier G. Patrick
The reaction of aldehydes (or ketones) with 2-alkoxy(or hydroxy)-3-alkenamines achieves a general and high-yielding synthesis of polysubstituted 3-acylpyrrolidines (eq 5-9). This tandem cationic aza-Cope rearrangement-Mannich cyclization reaction (eq 1) o
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