Synthesis of 2α-methyl- and 2β-methyl-3-(substituted methyl)cephalosporins, and 2,3-diexomethylenecepham

DOI: 10.1248/cpb.31.1482

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1482 - 1493 (1983)

Update date:2022-08-03

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Authors:

Mizokami

Fukase Fukase

Horii Horii

Kuwada Kuwada

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Article abstract of DOI:10.1248/cpb.31.1482

The stereoselective synthesis of 2α-methyl- and 2β-methyl-3-(substituted methyl)- cephalosporins via 2-methyl-3-formyloxymethylceph-2-em (5) and 2-methyl-3-acetoxymethylceph-2-em (16) from 2-methylene-3-acetoxymethylcephalosporin (1) is described. Reducti

Full text of DOI:10.1248/cpb.31.1482

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