A sequential RCM/fragmentation protocol towards chiral, stereodefined medium ring sesquiterpenoids. A carvone route to E- and Z-germacrenes

DOI: 10.1016/j.tetlet.2005.10.093

Source and publish data:

Tetrahedron Letters p. 8831 - 8835 (2005)

Update date:2022-08-04

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Authors:

Mehta, Goverdhan

Kumaran, R. Senthil

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Article abstract of DOI:10.1016/j.tetlet.2005.10.093

A short, flexible and enantioselective approach towards 10-membered germacratrienones, from the commercially available monoterpene chiron (-)-carvone, involving RCM and Grob-type fragmentation as the pivotal steps is delineated.

Full text of DOI:10.1016/j.tetlet.2005.10.093

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