Design and synthesis of novel oxazole containing 1,3-Dioxane-2-carboxylic acid derivatives as PPAR α/γ dual agonists

DOI: 10.1016/j.bmc.2008.06.050

Source and publish data:

Bioorganic and Medicinal Chemistry p. 7117 - 7127 (2008)

Update date:2022-07-30

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Authors:

Pingali, Harikishore

Jain, Mukul

Shah, Shailesh

Makadia, Pankaj

Zaware, Pandurang

Goel, Ashish

Patel, Megha

Giri, Suresh

Patel, Harilal

Patel, Pankaj

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Article abstract of DOI:10.1016/j.bmc.2008.06.050

A few novel 1,3-dioxane carboxylic acid derivatives were designed and synthesized to aid in the characterization of PPAR α/γ dual agonists. Structural requirements for PPARα/γ dual agonism of 1,3-dioxane carboxylic acid derivatives included the structural

Full text of DOI:10.1016/j.bmc.2008.06.050

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