Synthesis of 3(S)-acylamino-1-[(phenyl)-(1H-tetrazol-5-yL)amino]-2-azetidinones

DOI: 10.1016/S0040-4020(01)92153-2

Source and publish data:

Tetrahedron p. 2599 - 2608 (1983)

Update date:2022-08-05

Topics: Synthesis Acylation Column chromatography Yield NMR spectroscopy HPLC Chiral Resolution β-Lactam Coupling Reaction Tetrazole

Authors:

Atherton

Lambert Lambert

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Article abstract of DOI:10.1016/S0040-4020(01)92153-2

1-Phenyl-1-(1-benzyl-1H-tetrazol-5-yl)hydrazine has been synthesized from N¹-benzyloxycarbonyl-N²-phenylhydrazide and benzyl isothiocyanate. Coupling with N-(benzyloxycarbonyl)-L-serine 3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl ester

Full text of DOI:10.1016/S0040-4020(01)92153-2

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