BISABOLENE DERIVATIVES AND OTHER CONSTITUENTS FROM ACHILLEA ODORATA

Article abstract of DOI:10.1016/0031-9422(90)80187-L

From a hexane extract of the aerial parts of Achillea odorata, two nerolidol derivatives, (6E)-5,9-diacetoxynerolidol and (6E)-9-acetoxy-5-hydroxynerolidol, six bisabolene derivatives, 7,10-dihydroxy-bisabol-2,11-diene, 7,11-dihydroxy-bisabol-2,9E-diene, 1,10-diacetoxybisabol-2,11-diene, 7-hydroxy-11-hydroperoxybisabol-2,9E-diene, 7-hydroxy-10-hydroperoxybisabol-2,11-diene and (-)-α-bisabolol, as well as two flavones, 3,6,7,4'-tetramethoxy-5-hydroxyflavone and 3,6,7,3',4'-pentamethoxy-5-hydroxyflavone, have been isolated.Structures of the first three new terpenoids were established from their spectroscopic properties and by the use of some chemical correlations.