TRITERPENE GLYCOSIDES OF Astragalus AND THEIR GENINS. XXXVII. CYCLOARALOSIDE F FROM Astragalus amarus AND Astragalus villosissimus

Article abstract of DOI:10.1007/BF00630318

The glycosides of the plant Astragalus villosissimus Bunge have been studied.Four glycosides have been isolated from the roots of this plant, and two of them have been identified as β-sitosterol β-D-glucopyranoside and cycloaraloside C.The most polar glycoside, which has also been isolated from the roots of Astragalus amarus Pall., proved to be a new triterpene glycoside of the cycloartane series and has been called cycloaraloside F.It is a trioside of cyclosieversigenin containing two molecules of D-glucose and one molecule of D-apiose.On the basis of chemical transformations and spectral characteristics, the structure of cycloaraloside F has been established as 20R,24S-epoxycycloartane-3β,6α,16β,25-tetraol 3-O-2)-β-D-glucopyranoside> 25-O-β-D-glucopyranoside.