ON THE LITHIUM DIMETHYLCUPRATE INDUCED CONVERSION OF PROPARGYLIC ESTERS INTO ALLENES USING A STEROIDAL C/D FRAGMENT DERIVED FROM VITAMIN D3 AS A STEREOCHEMICAL PROBE.

Article abstract of DOI:10.1016/S0040-4039(00)87437-7

The reactions of (CH3)2CuLi with various C-8 epimeric propargylic esters derived from Grundmann's ketone, a C/D steroid fragment originating from vitamin D₃, lead to the corresponding allenes, the stereochemistry of which indicate a preferred a