Enantioselective syntheses of the indole alkaloid (+)-R-decarbomethoxytetrahydrosecodine and its enantiomer

DOI: 10.1016/0957-4166(96)00405-3

Source and publish data:

Tetrahedron Asymmetry p. 3091 - 3094 (1996)

Update date:2022-08-05

Topics:

Authors:

Amat, Mercedes

Pshenichnyi, Grigorii

Bosch, Joan

Molins, Elies

Miravitlles, Carles

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Article abstract of DOI:10.1016/0957-4166(96)00405-3

The alkaloid (+)-R-decarbomethoxytetrahydrosecodine (+)-1 has been synthesized by alkylation of (R)-3-ethylpiperidine with 3-(2-bromoethyl)-2-ethylindole (7). The required enantiopure piperidine was prepared by alkylation of the chiral non-racemic oxazolo

Full text of DOI:10.1016/0957-4166(96)00405-3

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Product name:(1'R,3S)-(-)-3-ethyl-1-(2'-hydroxy-1'-phenylethyl)piperidin-2-one

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