DIRECTED METALLATION OF TETRAMIC ACIDS: A NEW SYNTHESIS OF 3-ACYL TETRAMIC ACIDS

DOI: 10.1016/S0040-4039(00)86248-6

Source and publish data:

Tetrahedron Letters p. 4751 - 4754 (1983)

Update date:2022-08-04

Topics:

Authors:

Jones, Raymond C. F.

Peterson, Graeme E.

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Article abstract of DOI:10.1016/S0040-4039(00)86248-6

3-Acyl tetramic acids have been prepared by directed metallation at C-3 of the 4-O-methyl ethers of pyrrolidine-2,4-diones, reaction of the vinyl-lithium derivative with aldehydes, and oxidation and hydrolysis of the adducts.

Full text of DOI:10.1016/S0040-4039(00)86248-6

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