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Stereoselective Synthesis of α-Methylene-β-hydroxy-γ-alkoxy Esters from α-Alkoxy Aldehydes

DOI: 10.1039/c39830001112

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1112 - 1113 (1983)

Update date:2022-09-26

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Authors:

Banfi, LucaBanfi, Luca

Colombo, LinoColombo, Lino

Gennari, CesareGennari, Cesare

Scolastico, CarloScolastico, Carlo

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Article abstract of DOI:10.1039/c39830001112

The Reformatsky-type condensation between methyl and t-butyl 3-(N,N-dimethylamino)propionates (9) and (10) with α-alkoxy aldehydes, which has been studied on varying the protective group of the aldehyde, proceeds with good diastereoselectivity.

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