Journal of Medicinal Chemistry p. 605 - 609 (1984)
Update date:2022-08-04
Topics:
Rosowsky, Andre
Forsch, Ronald A.
Yu, Cheng-Sein
Lazarus, Herbert
Beardsley, G. Peter
n-Octyl, n-dodecyl, and n-hexadecyl α- and γ-esters of methotrexate (MTX) were compared with the previously described α- and γ-n-butyl esters and with MTX as inhibitors of dihydrofolate reductase (DHFR) and human leukemic lymphoblasts (CEM cells) in cultu
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