Substituted Benzamides with Conformationally Restricted Side Chains. 2. Indolizine Derivatives as Central Dopamine Receptor Antagonists

DOI: 10.1021/jm00117a008

Source and publish data:

Journal of Medicinal Chemistry p. 1708 - 1712 (1988)

Update date:2022-08-04

Topics:

Authors:

King, Frank D.

Hadley, Michael S.

McClelland, Christine M.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00117a008

The substituted benzamides metoclopramide (1) and clebopride (3) are stimulants of gastric molitity.They are also central dopamine receptor antagonists with 3 being the more potent.This is presumed to be due to an additional interaction of its N-benzyl gr

Full text of DOI:10.1021/jm00117a008

Products guided by the article

Product name:Benzeneacetonitrile, a-(2,2-diethoxyethyl)-2-fluoro-

Cas No:88897-66-9

R&D Labs maybe for 88897-66-9

Acros Pharmatech Limited

website:http://www.acrospharmatech.com

Contact:+1-3234804688

Address:Flat/RM 1502,Easey Commercial building 253-261 Hennessy Road,Wanchai，HongKong
ANHUI CHEM-BRIGHT BIOENGINEERING CO.,LTD

Contact:86-561-4080321

Address:No.8 Lieshan Industrial Zone of Huaibei
Zhonghao (dalian) Research and Design Institute of Chemical Industry Co., Ltd

Contact:+86 411 84674606

Address:201, Huangpu Road , Shahekou District, Dalian ,116023-China
TLS PHARMACEUTICAL CO.,LTD

Contact:0833-5590788/5590338/5590055

Address:Victory in the town of Red Star Village,Mount Emei City,industrial concentration area storage processing logistics parkpark
QUZHOU ZIO I/E CO.;LTD

Contact:13357117572

Address:No.149 Shiji dadao Road.

Relevant to this article

Palladium(0)-catalyzed intermolecular amination of unactivated Csp ³-H bonds

Doi:10.1002/anie.201102880
(2011)
A joint experimental and theoretical investigation on nonlinear optical (NLO) properties of a new class of push-pull spirobifluorene compounds

Doi:10.1002/ejoc.201000335
(2010)
2-acyl(aroyl)-1,1,3,3-tetracyanopropenides: II*. Synthesis of 2-[2-(alkylsulfanyl)-5-amino-2-aryl-4-cyano-2,3-dihydrofuran-3- ylidenepropanedinitriles by reaction with thiols

Doi:10.1134/S1070428011080070
(2011)
Imidazo[4,5-b]pyridine derivatives of potential tuberculostatic activity

Doi:10.1002/ardp.19913240212
(1991)
Novel Indanone Derivatives as Potential Imaging Probes for β-Amyloid Plaques in the Brain

Doi:10.1002/cbic.201200223
(2012)
Solid-phase synthesis of smac peptidomimetics incorporating triazoloprolines and biarylalanines

Doi:10.1021/co200078u
(2011)

Article Doi