Synthetic studies on areneolefin cycloadditions. VI. Two syntheses of (±)-coriolin

Article abstract of DOI:10.1016/S0040-4039(00)87859-4

The areneolefin photocyclization is shown to provide access to highly oxygenated natural products in an efficient and straightforward manner, as evidenced by the synthesis of coriolin via two separate routes; both proceed from 1-(2,6-dimethylphenyl)-1-acetoxy-2,2-dimethylpent-4-ene in 12 steps.