Histamine H2 receptor antagonists. 1. Synthesis of N-cyano and N-carbamoyl amidine derivatives and their biological activities.

DOI: 10.1021/jm00373a007

Source and publish data:

Journal of medicinal chemistry p. 849 - 857 (1984)

Update date:2022-07-29

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Authors:

Yanagisawa

Hirata Hirata

Ishii Ishii

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Article abstract of DOI:10.1021/jm00373a007

A large number of N-cyano amidine derivatives were prepared as potential histamine H2 receptor antagonists and evaluated for their inhibitory action on histamine-stimulated chronotropic response of isolated right atria from guinea pigs. Several selected c

Full text of DOI:10.1021/jm00373a007

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