Tumor Inhibitory Triazenes. 3. Dealkylation within an Homologous Series and Its Relation to Antitumor Activity

DOI: 10.1021/jm00373a011

Source and publish data:

Journal of Medicinal Chemistry p. 870 - 874 (1984)

Update date:2022-09-26

Topics:

Authors:

Wilman, Derry E. V.

Cox, Peter J.

Goddard, Phyllis M.

Hart, Leigh I.

Merai, Kanti

Newell, David R.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00373a011

The in vivo antitumor activity and in vitro metabolic dealkylation have been measured for an homologous series of 3-alkyl-1-(4-carbamoylphenyl)-3-methyltriazenes and have been compared with their partition coefficients.This investigation has shown that th

Full text of DOI:10.1021/jm00373a011

Products guided by the article

Product name:Benzamide, 4-(3-methyl-3-propyl-1-triazenyl)-

Cas No:89529-99-7

R&D Labs maybe for 89529-99-7

Tianjin SPHINX SCIENTIFIC LAB.

Contact:+86-022-66211289

Address:Tianda high-tech Park. No.80,the 4th Avenue
Zipont chem(wuhan）Tech co.，Ltd

Contact:+86-27-87587198

Address:wuhan
Xi'an Terra Biochem Co. Ltd.

Contact:0086-29-88315623

Address:S711, Innovation Bldg No.25 Gaoxin 1st Rd, Xian P.R of China 710075
Anhui Redstar Pharmaceutical Corp., Ltd

Contact:+86-563-5120837

Address:Jingxian Industrial Development Zone, Anhui , China
Shantou Baokang Pharmaceutical Co., Ltd.

Contact:+86-754-88873487

Address:5/F B Block Huangshan Bldg Huangshan Rd Shantou

Relevant to this article

A facile synthesis of fused aromatic spiroacetals based on the 3,4,3′,4′-tetrahydro-2,2′-spirobis(2H-1-benzopyran) skeleton

Doi:10.1016/j.tet.2006.04.026
(2006)
Carbonylative Tertiary Amide Synthesis from Aryl Iodides and Tertiary Amines via Oxidant-Free C?N Bond Cleavage Catalyzed by Palladium(II) Chloride in Polyethylene Glycol/Water

Doi:10.1002/adsc.201700317
(2017)
Copper-catalyzed double c-s bonds formation via different paths: Synthesis of benzothiazoles from n -benzyl-2-iodoaniline and potassium sulfide

Doi:10.1021/ol403638d
(2014)
Catalytic asymmetric addition of dialkylzinc reagents to α-aldiminoesters

Doi:10.1021/ol0602093
(2006)
The absolute configuration of 1-(3′,4′-dihydroxycinnamoyl) cyclopentane-2,3-diol from the Amazonian tree Chimarrhis turbinata

Doi:10.1021/np050522y
(2006)
Microwave-assisted synthesis of fused tricyclic pyrazino[1,2-a]indole derivatives

Doi:10.1007/s00706-014-1216-7
(2014)

Article Doi