Tumor Inhibitory Triazenes. 3. Dealkylation within an Homologous Series and Its Relation to Antitumor Activity

DOI: 10.1021/jm00373a011

Source and publish data:

Journal of Medicinal Chemistry p. 870 - 874 (1984)

Update date:2022-09-26

Topics:

Authors:

Wilman, Derry E. V.

Cox, Peter J.

Goddard, Phyllis M.

Hart, Leigh I.

Merai, Kanti

Newell, David R.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00373a011

The in vivo antitumor activity and in vitro metabolic dealkylation have been measured for an homologous series of 3-alkyl-1-(4-carbamoylphenyl)-3-methyltriazenes and have been compared with their partition coefficients.This investigation has shown that th

Full text of DOI:10.1021/jm00373a011

Products guided by the article

Product name:Benzamide, 4-(3-methyl-3-propyl-1-triazenyl)-

Cas No:89529-99-7

R&D Labs maybe for 89529-99-7

NEM CHEMICAL CO.，LTD

website:http://www.NEM.COM.CN

Contact:+86-393-4411771

Address:The west section of shengli Road,Puyang,Henan Province,China
Jiangxi Huashi Pharmaceutical Co., Ltd

Contact:+86-795-4509628

Address:Ningbo Ave., Fengtian Industrial Park, Fengxin Country, Jiangxi, China.
AUSHUN PHARMACEUTICAL TECHNOLOGY CO,.LTD

Contact:+86-25-86883560 15951806178

Address:14 Dayingbi, Zhujiang Rd. East, Nanjing, Jiangsu, China.
Jiaxing Barton Chemicals

website:http://www.chinabarton.com

Contact:+86-573-82719618

Address:No. 162 Fumin Road, Honghe Town,
Jiangxi Hito Chemical Co., Ltd.

Contact:+86-792-3170318

Address:No. 6, Tianhong Ave., Xinghuo Industry Park, Yongxiu, Jiujiang, Jiangxi, China

Relevant to this article

A facile synthesis of fused aromatic spiroacetals based on the 3,4,3′,4′-tetrahydro-2,2′-spirobis(2H-1-benzopyran) skeleton

Doi:10.1016/j.tet.2006.04.026
(2006)
Carbonylative Tertiary Amide Synthesis from Aryl Iodides and Tertiary Amines via Oxidant-Free C?N Bond Cleavage Catalyzed by Palladium(II) Chloride in Polyethylene Glycol/Water

Doi:10.1002/adsc.201700317
(2017)
Copper-catalyzed double c-s bonds formation via different paths: Synthesis of benzothiazoles from n -benzyl-2-iodoaniline and potassium sulfide

Doi:10.1021/ol403638d
(2014)
Catalytic asymmetric addition of dialkylzinc reagents to α-aldiminoesters

Doi:10.1021/ol0602093
(2006)
The absolute configuration of 1-(3′,4′-dihydroxycinnamoyl) cyclopentane-2,3-diol from the Amazonian tree Chimarrhis turbinata

Doi:10.1021/np050522y
(2006)
Microwave-assisted synthesis of fused tricyclic pyrazino[1,2-a]indole derivatives

Doi:10.1007/s00706-014-1216-7
(2014)

Article Doi