Tumor Inhibitory Triazenes. 3. Dealkylation within an Homologous Series and Its Relation to Antitumor Activity

DOI: 10.1021/jm00373a011

Source and publish data:

Journal of Medicinal Chemistry p. 870 - 874 (1984)

Update date:2022-09-26

Topics:

Authors:

Wilman, Derry E. V.

Cox, Peter J.

Goddard, Phyllis M.

Hart, Leigh I.

Merai, Kanti

Newell, David R.

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Article abstract of DOI:10.1021/jm00373a011

The in vivo antitumor activity and in vitro metabolic dealkylation have been measured for an homologous series of 3-alkyl-1-(4-carbamoylphenyl)-3-methyltriazenes and have been compared with their partition coefficients.This investigation has shown that th

Full text of DOI:10.1021/jm00373a011

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