
Tetrahedron Letters p. 4831 - 4834 (1982)
Update date:2022-08-05
Topics: Asymmetric synthesis Characterization Optimization Protecting groups Purification Retrosynthetic analysis Final steps Intermediate Synthesis Scale-up Ring Formation
Groot, Ae. de
Broekhuysen, M. P.
Doddema, L. L.
Vollering, M. C.
Westerbeek, J. M. M.
The total synthesis of (+/-)-colorata-4(13),8-dienolide (1), a sesquiterpene with a rearranged drimane skeleton, is described using 6β, 8aβ-dimethyl-5-methylene-3,4,4aα,5,6,7,8,8a-octahydro-1(2H)-naphtalenone (10) as a key intermediate.A new annelation me
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