Bioorganic and Medicinal Chemistry Letters p. 3147 - 3149 (2006)
Update date:2022-08-03
Topics:
Azoulay, Michel
Tuffin, Gerald
Sallem, Wafa
Florent, Jean-Claude
Many drugs induce severe side-effects caused by their lack of selectivity. One way to overcome this problem is to design a specific system which releases a free drug in a controlled manner. Herein we describe a new way to liberate a drug from a prodrug using the Staudinger ligation as the trigger.
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