A NOVEL APPROACH TO 4-BENZYLISOQUINOLINES

DOI: 10.1016/0040-4020(84)85123-6

Source and publish data:

Tetrahedron p. 215 - 220 (1984)

Update date:2022-08-03

Topics:

Authors:

Berger, U.

Burgemeister, Th.

Dannhardt, G.

Mayer, K. K.

Wiegrebe, W.

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Article abstract of DOI:10.1016/0040-4020(84)85123-6

The reaction of quinone methides with 3.4-dihydroisoquinoline or isoquinoline leads to benzylisoquinoline derivatives.NMR and ms investigations as well as chemical degradation prove that benzylation takes place at C-4 of the isoquinoline nucleus.Spectroscopic data are given for all new compounds.

Full text of DOI:10.1016/0040-4020(84)85123-6

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