Steroids. 2. Synthesis of C-18 functionalized steroids via the Smith-Hughes route.

DOI: 10.1021/jm00375a008

Source and publish data:

Journal of medicinal chemistry p. 1131 - 1137 (1984)

Update date:2022-08-05

Topics:

Authors:

Pillai Pillai

Murray Murray

Shooshani

Williams

Gordon Gordon

Wang Wang

Johnson Johnson

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Article abstract of DOI:10.1021/jm00375a008

The total synthesis of a series of racemic C-18 functionalized steroids was carried out in a search for novel estrogen-and/or progestin-receptor agonists or antagonists. The target compound 3,18-dihydroxyestra-1,3,5(10)-triene (2), 13-(2-oxopropyl)gona-4-

Full text of DOI:10.1021/jm00375a008

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