ONE-FLASK SYNTHESIS OF TRIACETALATED ALDOHEXOSES WITH 2,2-DIALKOXYPROPANE AND P-TOLUENESULFONIC ACID

Article abstract of DOI:10.1016/0008-6215(84)85110-1

2-Deoxy-D-arabino-hexose and some N-protected 2-amino-2-deoxy-D-glucose derivatives were each treated with 2,2-dimethoxy- or 2,2-dibenzyloxy-propane in 1,4-dioxane in the presence of p-toluenesulfonic acid at 60-70 deg.The major products were acyclic, dim