A reappraisal of the effect upon thymidine kinase of thymidine derivatives carrying large groups at the 5'-position

DOI: 10.1021/jm00374a018

Source and publish data:

Journal of Medicinal Chemistry p. 1044 - 1047 (1984)

Update date:2022-08-05

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Authors:

Barrie Barrie

Davies Davies

Stock Stock

Harrap Harrap

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Article abstract of DOI:10.1021/jm00374a018

Several thymidine derivatives with hydrophobic 5'-substituents, linked by chemically stable amide and ether links, were synthesized as potential thymidine kinase inhibitors. None of these was active nor were several derivatives of thymidine 5'-acetate, wh

Full text of DOI:10.1021/jm00374a018

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