Bioorganic and Medicinal Chemistry Letters p. 2491 - 2496 (1997)
Update date:2022-08-05
Topics:
Tomkinson, Nicholas C. O.
Sefler, Andrea M.
Plunket, Kelli D.
Blanchard, Steven G.
Parks, Derek J.
Willson, Timothy M.
A library of thiazolidinedione-fatty acid hybrid molecules was designed to probe the relationship between natural and synthetic PPAR ligands. Solid-phase synthesis of the library led to the identification of several high affinity PPARYγ ligands.
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