Synthesis and Pharmacological Evaluation of Indanpropionic Acids as Uterine Relaxants

DOI: 10.1021/jm00375a023

Source and publish data:

Journal of Medicinal Chemistry p. 1215 - 1219 (1984)

Update date:2022-08-05

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Authors:

Witiak, Donald T.

Hassan, Ahmed M.

Vecchio, Franziska R. Del

Brumbaugh, Richard J.

Rahwan, Ralf G.

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Article abstract of DOI:10.1021/jm00375a023

The PGF_2α antagonist 5,6-bis(benzyloxy)-1-oxo-2-propyl-2-indanpropionic acid (1) had previously been shown to provide significant protection against the abortifacient actions of PGF_2α in mice.To explore further structural concepts in

Full text of DOI:10.1021/jm00375a023

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