Carbohydrate Research p. 67 - 76 (1985)
Update date:2022-07-30
Topics:
Suami, Tetsuo
Tadano, Kin-Ichi
Iimura, Youichi
A newly isolated alkaloidal toxin, (-)-swainsonine <(1S,2R,8R,8aR)-1,2,8-trihydroxyoctahydroindolizine>, which exhibits an α-D-mannosidase inhibitory activity, has been synthesised stereoselectively in 15 steps starting from methyl 3-acetamido-2,4,6-tri-O-acetyl-3-deoxy-α-D-mannopyranoside.
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