Journal of Medicinal Chemistry p. 1212 - 1215 (1984)
Update date:2022-08-05
Topics:
Wierenga
Evans
Zurenko
An unusual acid-mediated rearrangement of o-nitrostyrene oxide afforded 1-(hydroxymethyl)-2,1-benzisoxazol-3(1H)-one which exhibited broad-spectrum antimicrobial and cytotoxic activity. A number of analogues were prepared by employing a modified zinc-redu
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Doi:10.1007/BF00908396
()Doi:10.1248/cpb.39.2443
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