Chemistry of Heterocyclic Compounds p. 204 - 209 (1984)
Update date:2022-08-02
Topics:
Mokrushin, V. S.
Pospelova, T. A.
Bakulev, V. A.
Golovina, E. F.
Nikolaeva, S. L.
Pushkareva, Z. V.
The acylation of 5(4)-aminoimidazole derivatives was studied.It is shown that acylation by means of carboxylic acid anhydrides and chlorides takes place at the amino group, whereas acylation by means of chlorocarbonic acid esters takes place at the nitrogen atoms of the imidazole ring.Methods for the selective introduction of a carbomethoxy group in the 1, 3, and 5 positions of the 5(4)-aminoimidazole-4(5)-carboxamide molecule were developed.
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