HETEROCYCLIC DERIVATIVES OF PURINES. 5. NUCLEOPHILIC SUBSTITUTION IN SERIES OF IMIDAZOPURINE DERIVATIVES

Article abstract of DOI:10.1007/BF00515651

The chlorination of 1,8-dimethyl-7-phenylimidazo<1,2-f>xanthine with an equimolar amount of PCl5 in POCl3 leads to 2,4-dichloro-8-methyl-7-phenylimidazo<1,2-f>purine.The possibility of substitution of the halogen atoms in reactions with nucleophilic reage