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9. Enantiomeric excess of 4 (99.7% ee) was determined by
HPLC analysis. This result indicates that the second
allylation also proceeds under control of the asymmetric
catalyst. For compound 4, see Ref. 5b.
Technology, Japan, and the Banyu Award in Synthetic
Organic Chemistry, Japan.
Supplementary data
General procedure of Pd-catalyzed asymmetric allylic
alkylation, other experimental procedures, and com-
pound characterization of all new compounds, can be
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