CREATION OF NOVEL CHIRAL SYNTHONS WITH ENZYMES AND APPLICATIONS TO NATURAL PRODUCT SYNTHESIS. 15. EFFICIENT INTRODUCTION OF CHIRAL CENTERS INTO CYCLOHEXANE RING.

DOI: 10.1016/S0040-4039(01)81230-2

Source and publish data:

Tetrahedron Letters p. 2557 - 2560 (1984)

Update date:2022-08-03

Topics:

Authors:

Kobayashi, Susumu

Kamiyama, Keiji

Iimori, Takamasa

Ohno, Masaji

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Article abstract of DOI:10.1016/S0040-4039(01)81230-2

The chiral half-ester 2 obtained by asymmetric hydrolysis of the symmetric diester 1 with pig liver esterase has been shown to be a versatile synthon for various chiral cyclohexane derivatives.

Full text of DOI:10.1016/S0040-4039(01)81230-2

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Product name:(1R,2R,4S,5S)-2-benzyloxycarbonylamino-4-iodo-7-oxo-6-oxabicyclo<3.2.1>octane

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