Tetrahedron p. 621 - 626 (1984)
Update date:2022-07-29
Topics: Catalyst Efficient Synthesis Experimental procedure Friedel-Crafts reaction
Gill, Melvyn
2-(Trimethylsilyl)benzofuran, available quantitatively from benzofuran itself, reacts rapidly with primary, secondary, and tertiary aliphatic carboxylic acid chlorides in the presence of titanium(IV) chloride at low temperature to afford the corresponding 2-acylbenzofurans in excellent yields.This approach offers significant synthetic advantage over existing routes to the title compounds.
View MoreBeijing ZhongDaXinHe Chemical Product Co.,Ltd(expird)
Contact:010-52876516
Address:tongzhoubeiyuan
Hebei Lead Bio-Chemicals Co., Ltd.
website:http://www.ldbiochem.com
Contact:+86-311-87826503
Address:481, Heping West Road, Shijiazhuang,China
Shanghai Korey Pharm Co.,Ltd.(expird)
Contact:021-61840961 021-61840962
Address:No.157,Zhuguang Rd, Qingpu, Shanghai, China
QINGDAO NEW FLOURISH INTERNATIOANAL TRADE CO., LTD.
Contact:+86 532 80861829
Address:No. 1, Yinchuan East Road, 266061, Qingdao, China
Hangzhou Gangjin Chemical Co.,Ltd.(expird)
Contact:+86-571-85109780
Address:707 Zhejiang Minhang Bldg., No.290 Zhongshan North Road, Hangzhou 310003, China
Doi:10.1021/jo01061a614
(1961)Doi:10.1039/c39860001692
(1986)Doi:10.1021/acs.orglett.1c02553
(2021)Doi:10.1021/ja01185a519
(1958)Doi:10.1021/acs.jmedchem.5b00043
(2015)Doi:10.1039/c5gc01040c
(2015)